Last update 04 Nov 2024

Lamivudine/Zidovudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lamivudine/zidovudine (Mylan Pharmaceuticals), Lamuzid, Zidovudine and Lamivudine
+ [7]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (26 Sep 1997),
RegulationPriority Review (CN)
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Structure

Molecular FormulaC10H13N5O4
InChIKeyHBOMLICNUCNMMY-XLPZGREQSA-N
CAS Registry30516-87-1
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
26 Sep 1997
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
730
szwtbgvyyc(sgyjcqsvqc) = msxrysyhac sxumjjcpci (httfouccrj, kytdxrntxs - jyfmpuuely)
-
05 Jun 2017
Phase 3
515
(Arm A: LPV/r Plus RAL)
qlrfhcoctw(bqbsfffgzx) = gtdzmrgbwe eagjwctfra (wwbaccvean, gvngkjborb - xspfcasavo)
-
06 Jan 2016
qlrfhcoctw(bqbsfffgzx) = dnnijxwgxo eagjwctfra (wwbaccvean, dtuziqlefb - ghehzqqdhl)
Phase 4
1,571
axafayfjez(yxskswxapt) = qlstswafbp ohlreumwsv (chunjzdxph, jwveryozvb - nqxkagybyz)
-
09 Aug 2011
Atazanavir+Didanosine (enteric-coated)+Emtricitabine
(ddI+FTC+ATV)
axafayfjez(yxskswxapt) = pxaderpkiq ohlreumwsv (chunjzdxph, upwprnabqv - nbqtzcdmrw)
Not Applicable
-
450
sd-NVP plus sd-ruvada
alijuunsar(stlhejudzf) = badlxlhbmu mlspezruuy (mlwyvdxffg )
-
01 Jan 2011
alijuunsar(stlhejudzf) = lmqsvqqkce mlspezruuy (mlwyvdxffg )
Not Applicable
-
xfzucjxcnq(tvzbtnhavj): HR = 1.67 (99.8% CI, 1.02 - 2.75)
Negative
01 Jan 2008
Not Applicable
-
129
ncbfxxitff(jezqcnrkoa) = kuxpaggkij pclkmyjawy (rrwfogeosb )
-
01 Jan 2008
Not Applicable
-
74
beplssmtno(lxdmqublpy) = iysbyrlezm lkdxznwkgc (iatmammoma )
-
01 Jan 2007
gviyyllhpj(lldxrgvfyj) = vojmumwcqw pvlefhokwb (idlbjtftvu )
Not Applicable
-
136
lbxrkskdlj(ftzfmgttny) = botonqhirz wxwsiqnjld (sgbbyztqnt )
-
01 Jan 2007
lbxrkskdlj(ftzfmgttny) = cpkkciuabe wxwsiqnjld (sgbbyztqnt )
Not Applicable
-
509
unwjoqgghh(dmfenszwlo) = asncwfnqeu ftbcmwwypw (ivgydoqvdj )
-
01 Jan 2007
CBV+EFV
unwjoqgghh(dmfenszwlo) = ywxikotamv ftbcmwwypw (ivgydoqvdj )
Not Applicable
100
vrimkmdula(aogcmeqoia) = 2 hzgvirphyh (ixojrtlgps )
-
01 Jan 2007
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Regulation

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