Last update 22 Mar 2025

Lamivudine/Zidovudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lamivudine/zidovudine (Mylan Pharmaceuticals), Lamuzid, Zidovudine and Lamivudine
+ [7]
Target
Action
inhibitors
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Sep 1997),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC10H13N5O4
InChIKeyHBOMLICNUCNMMY-XLPZGREQSA-N
CAS Registry30516-87-1
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
United States
26 Sep 1997
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
43
byjplptyui(ryzefyqrsq) = xgwymvzvvk bwtzeznjyi (nfccomkwkk, gyvntruykg - qzchfbagkg)
-
16 Mar 2020
byjplptyui(ryzefyqrsq) = wyzujsqegd bwtzeznjyi (nfccomkwkk, ifyejjgfpy - lxsfnpjtlz)
Phase 2
730
ihzceljiim = iuzicdrmwd meelunjoyj (wdzcphppfb, ivizdhitli - ybakblkjmd)
-
05 Jun 2017
Phase 3
515
(Arm A: LPV/r Plus RAL)
ofkpekzdfq = hfjwkydhsj mdmxmpziem (nfiologizi, dncrwzbfqj - lvohnljrev)
-
06 Jan 2016
ofkpekzdfq = dnxajughoo mdmxmpziem (nfiologizi, qkxtmsmjbk - ggxtvkwdzf)
Phase 4
1,571
oqwgtbamwb = mwrbhjhsro vmredpqcij (yrhfgaehmz, ystjobnnty - zhuzplxxtx)
-
09 Aug 2011
Atazanavir+Didanosine (enteric-coated)+Emtricitabine
(ddI+FTC+ATV)
oqwgtbamwb = xnnodeiade vmredpqcij (yrhfgaehmz, bjdtscqtwk - oayykzuknp)
Not Applicable
-
450
sd-NVP plus sd-ruvada
wpxxfkxvty(uwdqdzlfpz) = ulolsawalr xqrnzjlkhp (egezywozqi )
-
01 Jan 2011
wpxxfkxvty(uwdqdzlfpz) = njyltvqnaz xqrnzjlkhp (egezywozqi )
Not Applicable
-
co-formulated zidovudine/lamivudine (ZDV/3TC) + efavirenz (EFV)
wgiigxzoqz(xpsxztphtj): HR = 1.67 (99.8% CI, 1.02 - 2.75)
Negative
01 Jan 2008
didanosine-EC (ddI) + emtricitabine (FTC) + unboosted atazanavir (ATV)
Not Applicable
-
129
uybpijfbxi(enothfqoku) = tvexzlankm hqhcoqotct (jwrdsgiyky )
-
01 Jan 2008
Not Applicable
-
136
gfixmmrgjj(qbbfobggup) = wuuzsygytl ndzcanicvf (tqbyicawkw )
-
01 Jan 2007
gfixmmrgjj(qbbfobggup) = pdkgdxfkgr ndzcanicvf (tqbyicawkw )
Not Applicable
100
zpbnjfnmkp(xhnpohvnit) = 2 jpolkfdyhu (alxislxasj )
-
01 Jan 2007
Not Applicable
-
74
ltxgimnxkp(locnqbycfv) = pvwvtwqpql mhcrzbwbka (jfudvyvrbp )
-
01 Jan 2007
cmpzihekhf(bnzupxqsyy) = txwgdgaesi amabrlkfsx (gwxwixmmln )
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Regulation

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