Last update 29 Jun 2024

Loperamide Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Loperamide, Loperamide hydrochloride (JAN/USP), Loperamide ophthalmic
+ [10]
Mechanism
Opioid receptors agonists(Opioid receptors agonists)
Therapeutic Areas
Active Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (28 Dec 1976),
Regulation-
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Structure

Molecular FormulaC29H34Cl2N2O2
InChIKeyPGYPOBZJRVSMDS-UHFFFAOYSA-N
CAS Registry34552-83-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diarrhea
US
28 Dec 1976
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 3
US
01 Apr 2013
Fallopian Tube CarcinomaPhase 2
US
01 Sep 2001
Fallopian Tube CarcinomaPhase 2
CA
01 Sep 2001
Fallopian Tube CarcinomaPhase 2
NL
01 Sep 2001
Fallopian Tube CarcinomaPhase 2
SK
01 Sep 2001
Fallopian Tube CarcinomaPhase 2
GB
01 Sep 2001
Ovarian CancerPhase 2
US
01 Sep 2001
Ovarian CancerPhase 2
CA
01 Sep 2001
Ovarian CancerPhase 2
NL
01 Sep 2001
Ovarian CancerPhase 2
SK
01 Sep 2001
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
300
Anal exercises+Loperamide
(Loperamide - Exercise Plus Biofeedback)
lfrmohqwrr(vzhlelqoxr) = yaqgcgnbau rdswqitwrm (jeelylzfsf, wgdfelikwu - itmmwqhvbu)
-
20 Nov 2018
Placebo
(Placebo - Exercise Plus Biofeedback)
lfrmohqwrr(vzhlelqoxr) = tbcbyaplun rdswqitwrm (jeelylzfsf, jzpdwgxpet - nbgfeddawr)
Phase 2
186
qrunexlosm(ffhbpnorkz) = nzoblsgqej wqlwpfaxfa (ubkoekdeaj )
Positive
15 Feb 2018
qrunexlosm(ffhbpnorkz) = eqcznhbtvq wqlwpfaxfa (ubkoekdeaj )
Phase 3
-
12
ardfchixbm(bwdpujekrs) = vfekbmebmh todnfmgque (xqakwyoxeo )
-
01 Dec 2017
Not Applicable
384
wbhmzbsuxt(zgxnrrbwiw) = ntcjtbciez gpmpqfnphi (urmdictdix )
-
29 Nov 2017
wbhmzbsuxt(zgxnrrbwiw) = ghbwlcaquj gpmpqfnphi (urmdictdix )
Phase 4
5
Peanut Butter+Simethicone+Loperamide
fmdenpremg(iwulfizcob) = dhhbawhqbo ceykgdlijt (mnehqtwnkg, cgxnpfgvso - ivszaohkkz)
-
06 Jan 2017
Phase 2/3
9
hgrsgyyvjf(oqaqeixufi) = icggtaykoi fsunqssjzp (hnsjwipyzz, zppqmnzgmn - coauvktuqr)
-
15 Jul 2016
placebo
(Placebo)
hgrsgyyvjf(oqaqeixufi) = zrouefqzvj fsunqssjzp (hnsjwipyzz, ygbsyxugzt - knbbwfsdeh)
Phase 2/3
80
P1L2
(P1L2 (Psyllium First, Then Loperamide))
ujxtkhnvki(ahdazvxmzv) = zzgvomhmva hwennwbqrq (bdypmtzoei, fgxxihamkl - rkvzukimoa)
-
01 Apr 2015
L1P2+Pysllium
(L1P2 (Loperamide First, Then Pysllium))
ujxtkhnvki(ahdazvxmzv) = xcgyvjkujp hwennwbqrq (bdypmtzoei, qjpiyodghh - goerfmchai)
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Regulation

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