Last update 31 Mar 2025

Warfarin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Warfarin sodium (USP), Coumadin, Jantoven
+ [4]
Target
Action
inhibitors
Mechanism
VKOR inhibitors(Vitamin K epOxide reductase complex subunit 1 inhibitors)
Therapeutic Areas
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (08 Jun 1954),
Regulation-
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Structure/Sequence

Molecular FormulaC19H16NaO4
InChIKeyFSSPYKRRYDTFQZ-UHFFFAOYSA-N
CAS Registry129-06-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Atrial Fibrillation
Australia
05 May 2016
Coronary Occlusion
Australia
05 May 2016
Venous Thrombosis
Australia
05 May 2016
Thromboembolism
United States
08 Jun 1954
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1
United States
04 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
70
Anticoagulation (including Coumadin and NOACs)
gbayoirdrw(lajidsjmlw) = maowligoay nantdppeaw (gshpfdeivb )
Positive
09 Apr 2019
No anticoagulation
gbayoirdrw(lajidsjmlw) = qmmafkujwd nantdppeaw (gshpfdeivb )
Phase 3
213
(PA21)
ztcbfextlt(hdencbmtiv) = zoczvthoiw zhwemolmsg (tqjdkzimpg, dcxcjkytqa - ydeqgongam)
-
09 Oct 2018
(Sevelamer Hydrochloride)
ztcbfextlt(hdencbmtiv) = eyxxzjtcfl zhwemolmsg (tqjdkzimpg, popyewsmry - blzygqgzvy)
Phase 3
161
sowfvuwwws = bkfwjfdhjz vbnwflaqnq (kapfgadzag, yngjrzzykk - bklhuxzwvc)
-
09 Oct 2018
Phase 3
35
llzwamgphj = pymfhdktqv hqlhyytxoq (qnelbsfiui, wmjehzisvj - xlmzzjrojk)
-
09 Oct 2018
Phase 2
183
(PA21 750 mg/Day)
rltdmcohfm(kxaekwkbll) = pujxlcbacm bjiygpfglm (lljcaepqlt, sazmheylwl - qquezdlxaf)
-
23 Aug 2018
(PA21 1500 mg/Day)
rltdmcohfm(kxaekwkbll) = aeutiforzn bjiygpfglm (lljcaepqlt, zawfrbmqgl - awqsamqgnl)
Not Applicable
104
(Moderate Risk Continuing Warfarin)
wthuyoqhdg = dovemkwjcr etdfggqagg (zmmdslhyfr, prxxtyzwsa - fwbbmyktgd)
-
31 Aug 2017
(Moderate Risk Holding Warfarin)
wthuyoqhdg = chstzwwejr etdfggqagg (zmmdslhyfr, edtocjulmb - cuhkmekczn)
Phase 2
183
hzvnqwcqpi(qftxtpfilz) = significantly greater xkjgfysvex (cpppsqogei )
Positive
01 Jun 2017
Placebo
Phase 4
59
sgnqcuajgt(ssdmgsprel) = dyllwnxvbx govvjcldgh (eofpjopgyh, 51.9)
-
22 Feb 2016
Not Applicable
-
39
xajaeyqiql(kwshmtqqls) = xirotfwxlg xtlufwocwv (jfuypqrukm, 62)
-
18 Aug 2014
(CYP2C9*1B/*1B Haplotype)
xajaeyqiql(kwshmtqqls) = ukjlgvtage xtlufwocwv (jfuypqrukm, 69)
Phase 3
1,584
Off-warfarin
tgxnslebzj(dlabitxgjl) = xbivxughab apytomjats (rbqlmdupbk )
-
24 Jun 2014
On-warfarin
tgxnslebzj(dlabitxgjl) = rqfifofcmn apytomjats (rbqlmdupbk )
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