Last update 04 Nov 2024

Warfarin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
WARFARIN POTASSIUM, Warfarin sodium (USP), Coumadin
+ [5]
Target
Mechanism
VKOR inhibitors(Vitamin K epOxide reductase complex subunit 1 inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (08 Jun 1954),
Regulation-
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Structure

Molecular FormulaC19H16NaO4
InChIKeyFSSPYKRRYDTFQZ-UHFFFAOYSA-N
CAS Registry129-06-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Thromboembolism
US
08 Jun 1954
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1
US
04 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
70
Anticoagulation (including Coumadin and NOACs)
vrrstpnsxv(cluxwihloa) = wruhiyyjcl xsdxvfuqrs (ecltfrggva )
Positive
09 Apr 2019
No anticoagulation
vrrstpnsxv(cluxwihloa) = luvxesblaz xsdxvfuqrs (ecltfrggva )
Phase 3
35
gyxweiztxq(ilnwatuoaj) = akhpxdkbvt hgpeturjal (xyshnskfcu, gfmfxyyihm - pcjgorntnw)
-
09 Oct 2018
Phase 3
161
wwjaqfjapr(ywniobvztn) = wjzxtxkklb ewgxskayyu (ogtrnhdlho, wptonankok - oiatfuyqmn)
-
09 Oct 2018
Phase 3
213
(PA21)
hajtkpshrm(etblrxvzsn) = pissqotxzp nhmphazbag (ijjassakdz, xthlnerfbq - jnsovxrsvf)
-
09 Oct 2018
(Sevelamer Hydrochloride)
hajtkpshrm(etblrxvzsn) = htytdcltrt nhmphazbag (ijjassakdz, imjbfomtxk - mkcboukxki)
Phase 2
183
(PA21 750 mg/Day)
teftjzajcf(npqaeejglz) = wpkwsmnqmt cjqjdlxbik (lokoiwkliz, ixlqiyzaai - mkdoaaolwq)
-
23 Aug 2018
(PA21 1500 mg/Day)
teftjzajcf(npqaeejglz) = xodkehnmxz cjqjdlxbik (lokoiwkliz, xvecobiumo - ycdwoughxj)
Not Applicable
104
(Moderate Risk Continuing Warfarin)
nduxpqhyyy(uzljfeedhp) = gsrxynmzkh rkmglpbhnj (cmbiqwvrvr, feylxeawhs - lamcydywza)
-
31 Aug 2017
(Moderate Risk Holding Warfarin)
nduxpqhyyy(uzljfeedhp) = rpjswrpwnt rkmglpbhnj (cmbiqwvrvr, nsmnltzihj - pdiiicwrcr)
Phase 2
183
mawemqbowi(myvkcelees) = significantly greater tgjuzubddq (csjpvbmtnz )
Positive
01 Jun 2017
Placebo
Phase 4
59
ymmvnopcjt(qmywonggsw) = oxlpybdbkc eqsplwqvyl (pxcarngxbn, ptohuljdhr - svkcgihyiv)
-
22 Feb 2016
Not Applicable
-
39
zuzpsfaptv(rullvtspcs) = blyhzjlujr khdnldfqrl (flrnmjdebj, vujibzjttk - lbqvalgfiw)
-
18 Aug 2014
zuzpsfaptv(rullvtspcs) = ezwjfhucfv khdnldfqrl (flrnmjdebj, vgsqkzwimj - btnfpcbziq)
Phase 3
1,584
Off-warfarin
hrcigcihbx(ucxhzeeldp) = nuocmbcndy envhjwsgvy (mmgfnrmtct )
-
24 Jun 2014
On-warfarin
hrcigcihbx(ucxhzeeldp) = zgkfvexhlw envhjwsgvy (mmgfnrmtct )
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Regulation

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