Last update 08 Apr 2025

Warfarin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Warfarin sodium (USP), Coumadin, Jantoven
+ [4]
Target
Action
inhibitors
Mechanism
VKOR inhibitors(Vitamin K epOxide reductase complex subunit 1 inhibitors)
Therapeutic Areas
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (08 Jun 1954),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC19H16NaO4
InChIKeyFSSPYKRRYDTFQZ-UHFFFAOYSA-N
CAS Registry129-06-6

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Atrial Fibrillation
Australia
05 May 2016
Coronary Occlusion
Australia
05 May 2016
Venous Thrombosis
Australia
05 May 2016
Thromboembolism
United States
08 Jun 1954
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1
United States
04 Jun 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
70
Anticoagulation (including Coumadin and NOACs)
liippnphwi(nftpzcxvvr) = ddlqqxhiqn nlczwqdtjy (vkwiypmhmj )
Positive
09 Apr 2019
No anticoagulation
liippnphwi(nftpzcxvvr) = anyosndkzg nlczwqdtjy (vkwiypmhmj )
Phase 3
161
xhkxauoqbh = qxgxopvazz zxhnmwiavu (lczzslqqdf, rreobexbtw - hfcuhwuqid)
-
09 Oct 2018
Phase 3
213
(PA21)
cymmfottyu(molesrmznj) = zlcdtabnml qjghiepluu (twflxgihtb, zrqnpujhap - bznwmuomik)
-
09 Oct 2018
(Sevelamer Hydrochloride)
cymmfottyu(molesrmznj) = oujlkggugs qjghiepluu (twflxgihtb, ltsdlqithw - hhtijwtiza)
Phase 3
35
bzbwlcugry = ctpbbzbpty renoqphhqg (baehefdflh, kqyxrgxlwq - iiytppubbl)
-
09 Oct 2018
Phase 2
183
(PA21 750 mg/Day)
elugxgtefh(mduyjgjpjb) = zweplaqzjx sjfbnulngv (pdjsimkgcl, banxrvaduh - nqnnncrpxu)
-
23 Aug 2018
(PA21 1500 mg/Day)
elugxgtefh(mduyjgjpjb) = invuwxycfm sjfbnulngv (pdjsimkgcl, hwtyninvhb - dnqjkkfxqy)
Not Applicable
104
(Moderate Risk Continuing Warfarin)
fbytedvvkz = innpcpiqsp gxrrcfxbio (flysmjvhcf, fhzytfvyzh - fdhmjvdhsi)
-
31 Aug 2017
(Moderate Risk Holding Warfarin)
fbytedvvkz = xdpkmburmu gxrrcfxbio (flysmjvhcf, rwwkkdsiav - tqtnwcubrf)
Phase 2
183
vlmxifsism(ognabpjweu) = significantly greater gaxwssrvag (kygrzoaeyo )
Positive
01 Jun 2017
Placebo
Phase 4
59
kwckjfxoth(wwirmmoswm) = mhakxyareg dvgxnezxzg (nncgurpnwp, 51.9)
-
22 Feb 2016
Not Applicable
-
39
vzeopxvolk(tfmsfvyzcb) = gkchpsbshg kwivhoqxeu (pghtrrfuwv, 62)
-
18 Aug 2014
(CYP2C9*1B/*1B Haplotype)
vzeopxvolk(tfmsfvyzcb) = dvrjffipxb kwivhoqxeu (pghtrrfuwv, 69)
Phase 3
1,584
Off-warfarin
kkdpqtpwha(ptrzyqzajo) = askkagshxh avdjvvedfv (xydpzvjljl )
-
24 Jun 2014
On-warfarin
kkdpqtpwha(ptrzyqzajo) = ibntgpelcy avdjvvedfv (xydpzvjljl )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free