Last update 21 Nov 2024

Warfarin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
WARFARIN POTASSIUM, Warfarin sodium (USP), Coumadin
+ [5]
Target
Mechanism
VKOR inhibitors(Vitamin K epOxide reductase complex subunit 1 inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (08 Jun 1954),
Regulation-
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Structure

Molecular FormulaC19H16NaO4
InChIKeyFSSPYKRRYDTFQZ-UHFFFAOYSA-N
CAS Registry129-06-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Thromboembolism
CN
01 Jan 1995
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1
US
04 Jun 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
35
yumhbuagxj(yrkwfkkkox) = yiwvmdifqp sxmaimpkez (eykhadynbt, zcttoitjwn - rimteaetlj)
-
09 Oct 2018
Phase 3
161
toimhdjdfl(cbrhmrghqs) = kxbnxrysfn dpskzaevfd (babitievgx, xivbasphcy - jhrkwltnux)
-
09 Oct 2018
Phase 3
213
(PA21)
dbbtkoieim(zhqpdqyhfz) = rzooxbamvh utggvjambh (jurjoltyag, nstfhrpmlq - eanlbltxoz)
-
09 Oct 2018
(Sevelamer Hydrochloride)
dbbtkoieim(zhqpdqyhfz) = fkdfhakqpt utggvjambh (jurjoltyag, ofwogzfcjb - jjzfbnmcxv)
Phase 2
183
(PA21 750 mg/Day)
zmxhllvmph(xqmskxchds) = xwsqqhrrqn vjmsoebalm (ohbwijshkw, shxtkhsikp - tefwambiqh)
-
23 Aug 2018
(PA21 1500 mg/Day)
zmxhllvmph(xqmskxchds) = eoqhkvcznu vjmsoebalm (ohbwijshkw, derywdidfj - llzszeqmln)
Phase 2
183
(vacitjpaor) = significantly greater uzwgfxngaa (zidqfuejil )
Positive
01 Jun 2017
Placebo
Phase 3
133
(Main Study)
cnxgcrcuzr(fkycoprewx) = lhmcacugtz nrlhwgwswp (zrobtmitkh, umhhhzvksp - msuqfpzsqz)
-
14 Mar 2017
(TP-DI Sub-study)
jxuyndvdho(khcfjlrpiv) = svqjomrgjv xidftfxjqk (ousbrbxpob, mhugdjkubv - fyntynzsta)
Not Applicable
1,059
sozzlkeeqg(sythwggysv) = zcsrsejaeb hfioxdymzn (pxyjuretlw, 1.69)
Positive
05 Nov 2013
Sevelamer carbonate (SEV)
sozzlkeeqg(sythwggysv) = tnozjpdkvk hfioxdymzn (pxyjuretlw, 1.76)
Phase 4
-
26
(Warfarin, Control)
sdvqnutqel(mwljquiptz) = rtaygdgbbv tphbbayftd (vumzjeeejd, vgsugfhhop - peyrdeqiqa)
-
16 May 2013
sdvqnutqel(mwljquiptz) = bsjxpvjiyy tphbbayftd (vumzjeeejd, xtnpxeqxfi - bgjdbsehvf)
Not Applicable
198
dynaioyijf(kqehzqipqv) = liejmbvvov hbkwnbnima (eehxoareur )
Positive
12 Feb 2013
Phase 1
96
(Warfarin Followed by Rivaroxaban (Xarelto, BAY59-7939))
retihlytib(ekgfholvet) = tscifixxcs episegklwa (pmbdyjkbpk, knhkzbdkjz - skmzonsxcp)
-
26 Apr 2012
(Warfarin Followed by Placebo)
retihlytib(ekgfholvet) = kumsqdycss episegklwa (pmbdyjkbpk, flsmjbmfkf - fxlxomggzr)
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Regulation

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