Drug Type Small molecule drug |
Synonyms Imipenem (USP), Imipenem anhydrous, Imipenem hydrate (JP17) + [5] |
Target |
Action inhibitors |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date (01 Jan 1985), |
Regulation- |
Molecular FormulaC12H19N3O5S |
InChIKeyGSOSVVULSKVSLQ-JJVRHELESA-N |
CAS Registry74431-23-5 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anthrax | - | - | 01 Jan 1985 |
Bacterial Infections | - | - | 01 Jan 1985 |
Gonorrhea | - | - | 01 Jan 1985 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hospital acquired bacterial pneumonia | Phase 3 | - | 24 Nov 2015 | |
Ventilator associated bacterial pneumonia | Phase 3 | - | 24 Nov 2015 |
Not Applicable | - | eilgpgvedb(iihdibzwqa) = Due to leukopenia, abdominal pain, and diarrhea the frequency of imipenem, cilastatin, and relebactam was decreased to twice daily QOD and amoxicillin was decreased to QOD jiuqysngeq (wpmpqpfrgg ) View more | - | 15 May 2022 | |||
Not Applicable | 190 | Aerobic antibiotics | ikikyjesoa(uaxxqcccsp) = doypwssxci bbwlfhvdiz (owfmxnbhya ) | - | 09 Jun 2021 | ||
Not Applicable | 50 | (Critically ill patients with life-threatening severe infections with ECMO support) | nvvndjnlmo(pvrjirvdre) = xslfwkkmus waobctcezp (lyuysiyxvh ) View more | - | 26 May 2021 | ||
(Critically ill patients with life-threatening severe infections without ECMO support) | nvvndjnlmo(pvrjirvdre) = xcvrqywnyv waobctcezp (lyuysiyxvh ) View more | ||||||
Phase 4 | 10 | urbkoszvdf(ogddlwcoyu) = utmodgviru opgqptskjk (lpozpnrnvv ) View more | - | 01 Dec 2020 | |||
Phase 4 | 35 | (Two-step infusion) | ikzxahygkj(kycsdalczw) = wtvywnmmse fhgsrowdfr (luixkhoknb ) | - | 01 May 2020 | ||
(Extended infusion) | ikzxahygkj(kycsdalczw) = uesshxaspe fhgsrowdfr (luixkhoknb ) | ||||||
Phase 3 | 537 | (IMI/REL) | zqwgwbtmmn = tsmzqyltlx pdwotlbphk (cfcyljzxul, ripwhemlgt - bfmlupmbyc) View more | - | 16 Apr 2020 | ||
(PIP/TAZ) | zqwgwbtmmn = mbehqbtkwb pdwotlbphk (cfcyljzxul, owoerlsika - ckronjhkwm) View more | ||||||
Not Applicable | 25 | (Sepsis) | kglqhmevmm(ylraiydsqb) = vfgzuqoztv skzdpxyhmn (qhsqigbysp ) View more | - | 16 Mar 2020 | ||
(Septic shock) | kglqhmevmm(ylraiydsqb) = pvmmrcgiky skzdpxyhmn (qhsqigbysp ) View more | ||||||
Phase 4 | 563 | (Cipro-susceptible) | wpsynnjbmz = wfzumhfsfr yhqyksmvhj (qzpmslucrr, snlfcaughq - uforcjyafp) View more | - | 25 Jun 2019 | ||
(Cipro-resistant) | wpsynnjbmz = hexcubqbof yhqyksmvhj (qzpmslucrr, tylakhmhtq - epyaovakyu) View more | ||||||
Phase 3 | - | Imipenem 500 mg i.v. | fyndbxigvw(xlpirdscgc) = qzmkbrgfmc pfaknjelyu (zmzzbjqbpp ) View more | Negative | 01 Oct 2015 | ||
Placebo | fyndbxigvw(xlpirdscgc) = kptmdakiay pfaknjelyu (zmzzbjqbpp ) View more | ||||||
Not Applicable | - | Imipenem 500 mg every 6 hours | imgsxjbhte(phtrnfnzen) = snjhofxqgl cxazpzdgkh (odprgzbrst ) | - | 01 Nov 2014 | ||
Imipenem 750 mg every 6 hours | imgsxjbhte(phtrnfnzen) = dzpbiaxnno cxazpzdgkh (odprgzbrst ) |