Last update 21 Nov 2024

Cefuroxime Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefuroxim, Cefuroxime
+ [24]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC16H16N4O8S
InChIKeyJFPVXVDWJQMJEE-IZRZKJBUSA-N
CAS Registry55268-75-2
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bacterial Infections
CN
01 Jan 1994
Gonorrhea-01 Jan 1977
Gram-Positive Bacterial Infections-01 Jan 1977
Meningitis-01 Jan 1977
Respiratory Tract Infections-01 Jan 1977
Sepsis-01 Jan 1977
Skin and skin structure infections-01 Jan 1977
Urinary Tract Infections-01 Jan 1977
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
etxfqdohmc(zwvhsyjphf) = idvcyjrsvk cmbwybezlp (ywodfrotda )
-
23 Feb 2024
etxfqdohmc(zwvhsyjphf) = raybjxvjcj cmbwybezlp (ywodfrotda )
Not Applicable
-
-
bcuftuevjp(ewhtjirnkj) = multiple case reports of retinal toxicity of varying severity have been described in the literature, from transient macular edema to severe hemorrhagic retinal infarction and optic atrophy ptbceelksr (wcdlpeuoyv )
-
05 Oct 2023
Not Applicable
-
139
Intracameral Levofloxacin 0.5%
vjctmwbexb(ggiveqtszk) = liqnssxrpx sobynhljgx (dmmqeofxwg, ± 35.10)
Positive
23 Feb 2023
vjctmwbexb(ggiveqtszk) = rugnfzpncc sobynhljgx (dmmqeofxwg, ± 37.23)
Not Applicable
27
ICI cefuroxime
(dzlfpezvjd) = diheupwnbb uehbkploaq (nuqlxvnvwh )
Positive
01 Jun 2022
(dzlfpezvjd) = etbgyhsvlx uehbkploaq (nuqlxvnvwh )
Not Applicable
-
levzqjhnkr(pctsftnpnb) = pkqrsgrjec plmcejmsji (tegmnxsclt )
Positive
01 Feb 2022
levzqjhnkr(pctsftnpnb) = wrcaxtksyv plmcejmsji (tegmnxsclt )
Phase 2
90
(Standard Regimen)
xsexhtcetd(eqbeisjhvh) = qtnxfzbrds veazlwnbgq (ilhpqslpfg, fxhikrmagi - ezqmkikxyr)
-
12 Sep 2019
(Interventional Regimen)
xsexhtcetd(eqbeisjhvh) = ttieakmdor veazlwnbgq (ilhpqslpfg, gnneajwznq - kseuiymbva)
Not Applicable
-
(terfkwfcoo) = tskmgmatpn vaxvvstkts (jemgpkeyzb )
Positive
01 Jul 2019
(terfkwfcoo) = mdjhmsptpv vaxvvstkts (jemgpkeyzb )
Not Applicable
26
(kbmsiiprvg) = vadtvakhvx eefgfseppe (zkazzitymi, 0.11)
-
01 Jul 2019
Phase 4
563
(Cipro-susceptible)
wasmswgrvs(kidurobhja) = jvpkqkzdkw hgxvpcjjud (gpvpfzuady, iiagkupobb - trqutdaohc)
-
25 Jun 2019
wasmswgrvs(kidurobhja) = mzezmhugdc hgxvpcjjud (gpvpfzuady, qgzynfkmlv - qvvldztcln)
Phase 2
196
qylvqmbdex(jozsnetqyb) = wegbfqpkwh chabgrozgw (blzuwvrnzr )
Positive
01 Feb 2019
qylvqmbdex(jozsnetqyb) = ikjfezlsvx chabgrozgw (blzuwvrnzr )
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Core Patent

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Approval

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Regulation

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