uniQureN.V.,announces that their AMT-260 Gene Therapy candidate, developed for the treatment of Refractory Mesial Temporal Lobe Epilepsy, has received approval for the Investigational New Drug Application from the FDA.
Angiotensin-converting enzyme 2 (ACE2) is a key enzyme in the Renin-Angiotensin System (RAS), acting as a regulating factor for the ACE-Angiotensin II (Ang II)-Ang receptor I (AT1) axis, maintaining the balance of the RAS system.
X4 Pharmaceuticals has submitted a New Drug Application (NDA) to the FDA for the approval of once-daily oral mavorixafor in the treatment of WHIM syndrome.
On September 6, 2023, Eli Lilly has registered a Phase III clinical trial (Study Code: ATTAIN-2) of the oral small molecule GLP-1R agonist Orforglipron (LY3502970) for the treatment of type 2 diabetes patients with obesity or overweight.