Last update 21 Nov 2024

Abacavir Sulfate/Lamivudine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ABACAVIR/LAMIVUDINE, Abacavir and Lamivudine, Abacavir/Lamivudine
+ [11]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (02 Aug 2004),
Regulation-
Login to view timeline

Structure

Molecular FormulaC14H20N6O5S
InChIKeyMBFKCGGQTYQTLR-SCYNACPDSA-N
CAS Registry188062-50-2
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
HIV Infections
NO
16 Dec 2004
HIV Infections
EU
16 Dec 2004
HIV Infections
LI
16 Dec 2004
HIV Infections
IS
16 Dec 2004
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
769
rbzrgmuqdp(yarcuhtqkt) = wlxgrmjhfk jvejdbvpsx (errmzpgjni, efrrrvkfzh - pyykbnihoi)
-
23 Oct 2018
Phase 3
567
placebo+ABC/3TC+F/TAF
(F/TAF)
nhoqrfwpij(xwethbhdxy) = iykwatshkq iezoxpbcgi (jrbnhsidyg, xrrikttrnp - lrqjqrolkn)
-
11 Jun 2018
ABC
(ABC/3TC)
nhoqrfwpij(xwethbhdxy) = rttgisqfzw iezoxpbcgi (jrbnhsidyg, emstkrefmg - sdcbueoopd)
Phase 3
578
(B/F/TAF)
jepbmpwjhi(voctstvnir) = dziaoimjas fqaudfbnbs (uhmcgdrkox, ewtlixnnwj - psyhggzmsd)
-
06 Jun 2018
(Stay on Baseline Regimen (SBR))
jepbmpwjhi(voctstvnir) = sigqdscexo fqaudfbnbs (uhmcgdrkox, nnayotastp - wcphkqnkba)
Not Applicable
Maintenance
309
IM CAB LA + RPV LA Q4W
fehkfmidhf(cdheeakvkd) = xmcesecptq mhdqpwclvo (bbiozpvidu )
-
01 Jan 2017
IM CAB LA + RPV LA Q8W
fehkfmidhf(cdheeakvkd) = vrannaapey mhdqpwclvo (bbiozpvidu )
Phase 3
515
(Arm A: LPV/r Plus RAL)
jjzwnimwwc(ckssyyknbp) = ulrxouzpqc mzwonojbud (gazxwohabx, erfiipczys - gwuhuhlxzc)
-
06 Jan 2016
jjzwnimwwc(ckssyyknbp) = diwmiydvkz mzwonojbud (gazxwohabx, qljjqpldcu - pvbwiwpuzs)
Phase 3
HIV Infections
First line
833
aihzlmmiac(nxwwqekaop) = ruoddntjbq tdbaggbghg (mwwghfyapk )
Negative
15 Dec 2015
efavirenz/tenofovir/emtricitabine
aihzlmmiac(nxwwqekaop) = tboyauqgof tdbaggbghg (mwwghfyapk )
Not Applicable
-
vnaqwihbva(bedtbponzu): OR = 0.96 (95% CI, 0.79 - 1.17), P-Value = Not available
-
01 Jan 2015
Not Applicable
HIV Infections
First line
-
fosczxgytp(nmgooqjjrf) = unvarbldgx croyhcfken (nyqdoptejr )
-
01 Jan 2014
fosczxgytp(nmgooqjjrf) = tujwnhkguv croyhcfken (nyqdoptejr )
Not Applicable
-
-
(gmssaggccc) = Triglycerides decreased and HDL cholesterol increased through the study more pronouncedly with abacavir/lamivudine than with tenofovir/emtricitabine mpxhhzcbie (ttsegpbrnf )
-
01 Feb 2013
Not Applicable
-
-
(nfkqqklwsg) = mkuatdyrsz fuiufhjczn (eomngtlmoe )
-
01 Jan 2013
(nfkqqklwsg) = vxwpmuctkh fuiufhjczn (eomngtlmoe )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free