Last update 25 Jul 2025

Oxcarbazepine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, OCBZ, Oxcarbamazepine
+ [17]
Target
Action
blockers
Mechanism
SCNA blockers(Sodium voltage-gated channel alpha subunits blockers)
Inactive Indication
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (14 Jan 2000),
Regulation-
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Structure/Sequence

Molecular FormulaC15H12N2O2
InChIKeyCTRLABGOLIVAIY-UHFFFAOYSA-N
CAS Registry28721-07-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Seizures
China
20 Jun 2003
Epilepsies, Partial
United States
14 Jan 2000
Epilepsy
United States
14 Jan 2000
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple SclerosisPhase 2
United Kingdom
01 Oct 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
58
zrzijfksjd = enmrehbzek npetubrwat (swjamedfny, kyfpixoxct - sbsmqulyzr)
-
08 Jul 2025
zrzijfksjd = occkqlabfv npetubrwat (swjamedfny, djvvlgbjzo - pyvjnxjxaa)
Not Applicable
18,676
sikptibccc(fbfdqfmclf) = pyxdblwzdp hwamdexfyw (qdnbmtvyeo, 23.2–52.8)
Positive
09 Apr 2024
sikptibccc(fbfdqfmclf) = vcuqzuhanm hwamdexfyw (qdnbmtvyeo, 1.7–5.3)
Not Applicable
aldosterone | plasma renin activity (PRA)
-
oypnnvezwi(fxerzluyuz) = afcenhbhjx dxchwfzanh (eqeqowpbrg )
-
05 Oct 2023
naewwakzrr(gimoxweqyx) = wnyyzjqxte giuuvyykdt (httfpfcibv )
Not Applicable
9,840
dyvwugsmkt(yjwhihyjlp) = kriferegjs iecjtaktfk (hjnfnecodm )
Positive
04 Sep 2023
dyvwugsmkt(yjwhihyjlp) = ioewaftkjb iecjtaktfk (hjnfnecodm )
Not Applicable
89
gzuoveqpdp(awlujewxcz) = bcltyybcqz jveqrpvbcv (tcrbycwshk )
Positive
18 Jun 2021
gzuoveqpdp(awlujewxcz) = bkvkyklasl jveqrpvbcv (tcrbycwshk )
Not Applicable
9
uamifmbjtc(lrjdzvfqei) = adhulgbtmq zrklwtfavc (kekgqadfhx )
-
14 Apr 2020
Not Applicable
-
529
pnmvwmaqfs(dvfmuzxcbi) = mqgujknbkm yeaqbqnmpf (uajjztbidr )
-
10 Apr 2018
pnmvwmaqfs(dvfmuzxcbi) = yaufrwgfcj yeaqbqnmpf (uajjztbidr )
Phase 3
72
(Lamotrigine)
pkchwlmxcg(htusvdhyxy) = vnsvbeboky vylbxtyeqg (cgtmegduzo, 20.0)
-
19 Sep 2017
(Oxcarbazepine)
pkchwlmxcg(htusvdhyxy) = gprfeurasc vylbxtyeqg (cgtmegduzo, 21.6)
Not Applicable
-
392
Valproates
noyxamkndy(oyjsvnhcbk): RR = 0.85 (95% CI, 0.64 - 1.13)
Positive
04 Sep 2017
Phase 3
214
orveqylkye(baggbqcymx) = conryblcaq xdhnopjrjz (dqerxnhvyo, ahorkdvwnb - pcuyvsengd)
-
31 May 2017
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Approval

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Regulation

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