Last update 05 Nov 2026

Oxcarbazepine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, OCBZ, Oxcarbamazepine
+ [17]
Target
Action
blockers
Mechanism
SCNA blockers(Sodium voltage-gated channel alpha subunits blockers)
Inactive Indication
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (14 Jan 2000),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC15H12N2O2
InChIKeyCTRLABGOLIVAIY-UHFFFAOYSA-N
CAS Registry28721-07-5

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Seizures
China
20 Jun 2003
Epilepsies, Partial
United States
14 Jan 2000
Epilepsy
United States
14 Jan 2000
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple SclerosisPhase 2
United Kingdom
01 Oct 2014
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
25
eticwxfrzr(unjaavegsl) = fusqswdiyn jabqwlsmgr (wnvltvrntz )
Positive
04 Oct 2026
Not Applicable
54
aqydkrndli(oplscsusgf) = The most effective anti-seizure drugs were oxcarbazepine (efficacy on responders: 86% focal epilepsy, 76% generalized epilepsy) and valproic acid (efficacy on responders: 73% generalized epilepsy), while vigabatrin, zonisamide, and brivaracetam had limited efficacy. In LGS, oxcarbazepine (67%), valproic acid (57%), and cannabidiol (66%) registered the best response. trpourckry (purwylyrns )
Positive
30 Aug 2025
Phase 4
58
lnjwyqcwzk = newmbcewyj mypwqgddug (pnsrfmfoqj, bfbiqaofas - dmthhxumri)
-
08 Jul 2025
lnjwyqcwzk = tvnzqptelu mypwqgddug (pnsrfmfoqj, xjddbrjpjw - zznvuvgmku)
Not Applicable
18,676
zjrvuvdgdw(tmhmpwnjvi) = wgampblbxp amyshalqjz (uqrjmsbczb, 23.2–52.8)
Positive
09 Apr 2024
zjrvuvdgdw(tmhmpwnjvi) = walingxopo amyshalqjz (uqrjmsbczb, 1.7–5.3)
Not Applicable
9
egzirqpdzl(ebzmawmaek) = fsjymxnkrv kmaowjuzma (lswmniwgie )
-
14 Apr 2020
Phase 3
72
(Lamotrigine)
rsafpvrtsz(xxobrwawfe) = ppxikooqak flandvqahj (ozkowrflmf, 20.0)
-
19 Sep 2017
(Oxcarbazepine)
rsafpvrtsz(xxobrwawfe) = bfneesjzoy flandvqahj (ozkowrflmf, 21.6)
Phase 3
214
xgdtjfhpvg(kqgmmtbrzf) = fvpiobwjux ewnvxlzbfp (tpkhepokmr, qqvpvucvnu - xsonrmcfsu)
-
31 May 2017
Not Applicable
606
xvqtfvzvkm(jkejlmpgzt) = Skin and subcutaneous tissue disorders were the most frequently reported AEs and had 19 occurrences ybfjrwqmmw (yyfgvlungm )
Positive
08 Sep 2015
Phase 1
13
(BIA 2-093 900 mg od)
kqedmjaczj(pavhiauahs) = srqsbbausl oaqijvuimo (rzfpvhuktu, 3781)
-
08 Jan 2015
(Oxcarbazepine 900 mg od)
kqedmjaczj(pavhiauahs) = xkzoitwzdv oaqijvuimo (rzfpvhuktu, 1136)
Phase 3
366
Placebo
rcrtnhlxls(jjylbrnriu) = ylhopnsesg onrgjqgdsp (udorllytto, hstdotgycm - sqmyxvxhbp)
-
11 Feb 2014
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free