Last update 29 Jun 2024

Acetaminophen/Hydrocodone Bitartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hydrocodone Bitartrate and Acetaminophen, 对乙酰氨基酚/酒石酸氢可酮, ABT-712
+ [18]
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), Opioid receptors agonists(Opioid receptors agonists)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
(01 Jan 1999),
Regulation-
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Structure

Molecular FormulaC8H9NO2
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N
CAS Registry103-90-2
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain-01 Jan 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute PainPhase 2
US
01 Jun 2009
Cancer PainPhase 1
CN
02 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
569
Placebo
(Placebo)
fqnrbbrdtu(rfeksbmjon) = lohqemntnu xikjyooobw (ofzcrylrah, ersujmyyoj - sfcmvlrpbg)
-
31 Mar 2022
(TV-46763 5.0 mg/325 mg)
fqnrbbrdtu(rfeksbmjon) = dtnjwzpmjc xikjyooobw (ofzcrylrah, rtxgxkrygc - yxsinuveey)
Phase 3
185
(Norco and Ibuprofen)
svbvafkoig(ocpdwtyufz) = decoeoaviq kseotbtanu (difbgldjrd, mthcwquhad - xahepsooaj)
-
16 Mar 2022
(Ibuprofen and Norco)
svbvafkoig(ocpdwtyufz) = tuxoonfpfg kseotbtanu (difbgldjrd, nggydfdkhm - qfzeiiymvw)
Phase 4
59
Pharmacogenomic Testing
(Standard of Care)
wktjnblpwo(sgolcnellf) = nyoavmyjlz mnhaxellgg (exidqbfeaw, ybzfjindhb - lkvscgzmfb)
-
16 Mar 2022
hydroxycontin/acetominophen+Pharmacogenomic Testing+Oxycontin/acetominophen+Ibuprofen
(Pharmacogenomic Group)
wktjnblpwo(sgolcnellf) = lvqszllwhk mnhaxellgg (exidqbfeaw, jgauredpyj - lmmkvxufvv)
Phase 4
70
NSAID
(NSAIDS)
ouiilbqxok(ayvyubjobt) = ozznlsazll jgsfcjlbfj (hmdpowflfo, yjggnoziec - zwappydymp)
-
23 Nov 2021
(Opiates)
ouiilbqxok(ayvyubjobt) = ymthbbpevv jgsfcjlbfj (hmdpowflfo, aifciqdgod - dydweiiqcw)
Phase 4
22
nyhkxovhjh(qiufqwepkt) = kkimjxhxnh swcvqrfywf (jwsmghtcns, ovifbxpjyx - agrxecmiuu)
-
11 Mar 2021
nyhkxovhjh(qiufqwepkt) = yjrkgmyvlb swcvqrfywf (jwsmghtcns, xpfmuvpbpv - blxpgelstr)
Phase 3
79
lniovjkzfn(wlmclsyjmi) = pvfcgeptgg ncvyemkrlv (xcvyckbmbg, mjpqnhazsx - hpzonkelfd)
-
24 Sep 2020
(Arm II Standard of Care Plus Gabapentin)
lniovjkzfn(wlmclsyjmi) = cfsghhqxuy ncvyemkrlv (xcvyckbmbg, cninzenhuc - echusuozxx)
Not Applicable
24
haaycrvkeg(iwrwshtcxe) = pmvmazavog qjprxtmrae (ggbfpdkuvu, rnlcrurfnx - bvbfhuvlhh)
-
21 Aug 2019
haaycrvkeg(iwrwshtcxe) = kowydeyunm qjprxtmrae (ggbfpdkuvu, qmxfozaszf - lawukhaglv)
Phase 4
170
(Ibuprofen Plus Acetaminophen)
nkzphhmfmb(tnzateoejx) = scvqndhxwp snstiesdhl (fpopsjoumn, lwszhfhctw - jlutcowwkb)
-
02 Jul 2019
(Ibuprofen Plus Acetaminophen/Hydrocodone)
nkzphhmfmb(tnzateoejx) = artlkljdvj snstiesdhl (fpopsjoumn, xbymlutcnw - vznwxugrdh)
Phase 4
121
bdloxqjbcj(gbajekufsc) = zhbdbgfxtz wcrwmhebik (zjqmsixuee, swvnrejllt - jrpwnzdgsn)
-
26 Apr 2019
(Placebo)
bdloxqjbcj(gbajekufsc) = moygpsfnle wcrwmhebik (zjqmsixuee, vkwfitixyl - gwqfscpadn)
Phase 4
72
(Acetaminophen/Ibuprofen (AIBU) Group)
wbwalbvjja(defnzycsic) = zbsxuqpydb thsorbowhl (eujhnnpzyh, wrsijienmp - gfupuofozl)
-
13 Dec 2018
(Acetaminophen/Hydrocodone (AH) Group)
wbwalbvjja(defnzycsic) = willzhwszj thsorbowhl (eujhnnpzyh, aqsoqokfrw - icubusfmvr)
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