CDK4 inhibitors can inhibit the formation of complexes between CDK4 and cyclin D, block ATP binding, thereby severing upstream growth signals, and prevent the transition from G1 to S phase.
This article summarized the latest R&D progress of Triclabendazole, the Mechanism of Action for Triclabendazole, and the drug target R&D trends for Triclabendazole.
The 2023 ESMO Congress marked a pivotal moment with the disclosure of a clinical trial for Osimertinib mesylate in EGFR-mutated NSCLC patients, opening avenues for further increases in its clinical efficacy.
The overexpression of the anti-apoptotic factor Myeloid Cell Leukemia 1 (MCL-1), caused by the activation of CDK9, will lead to the transformation of malignant tumor cells. Therefore, inhibiting CDK9 will downregulate MCL-1, thereby suppressing tumor growth.
This article summarized the latest R&D progress of Raloxifene Hydrochloride, the Mechanism of Action for Raloxifene Hydrochloride, and the drug target R&D trends for Raloxifene Hydrochloride.
The recent ESMO Congress presented noteworthy clinical trial results of Givastomig, paving the way for a detailed exploration of its therapeutic potential in solid tumors.