AMPK is a critical metabolic regulator, responsible for maintaining and restoring energy balance at the cellular and physiological levels. Studying AMPK targets and their microenvironment helps clarify how AMPK restores energy homeostasis.
This article summarized the latest R&D progress of Nitroxoline, the mechanism of action for Nitroxoline, and the drug target R&D trends for Nitroxoline.
REGENXBIO Inc. reveals positive additional results from ongoing Phase II ALTITUDE® study. The study pertains to ABBV-RGX-314, expected for treating diabetic retinopathy except center-involved diabetic macular edema, and is given through in-office suprachoroidal delivery.
AKT (Protein Kinase B), a pivotal player in PI3K/AKT/m-TOR signaling pathway, is a prospective drug target clinically. Its activation is crucial for cell survival and growth, implicating in tumorigenesis and metastasis. Research indicates AKT over-activation in over 50% of tumors.
This article summarized the latest R&D progress of Norelgestromin, the Mechanism of Action for Norelgestromin, and the drug target R&D trends for Norelgestromin.
Ankyra Therapeutics has published encouraging preclinical results for the combined use of ANK-101, a new anchored immune therapy, and cytotoxic chemotherapy in a head and neck cancer model.
Scholar Rock shares fresh results from its phase 1 DRAGON trial, indicating anti-tumor potential in patients with metastatic ccRCC who are resistant to Anti-PD-1. The data also backs the ongoing tolerability of SRK-181.
This article summarized the latest R&D progress of Oxiconazole Nitrate, the Mechanism of Action for Oxiconazole Nitrate, and the drug target R&D trends for Oxiconazole Nitrate.
Acetylcholinesterase (AChE), the primary cholinesterase in the body, is an enzyme catalyzing the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters.
Cue Biopharma shares encouraging results from Phase 1 studies for CUE-101 for Head and Neck Cancer, and CUE-102 for Wilms' Tumor 1 related cases, at the SITC 2023 event.