Drug Type Small molecule drug |
Synonyms Azasetron Hydrochloride and Sodium Chloride, Granisertron Hydrochloride, Granisetron HydrochIoride + [48] |
Target |
Mechanism 5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (29 Dec 1993), |
Regulation- |
Molecular FormulaC18H25ClN4O |
InChIKeyQYZRTBKYBJRGJB-WQTKJZBYSA-N |
CAS Registry107007-99-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00677 | Granisetron Hydrochloride | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Radiation-induced nausea and vomiting | JP | 22 Dec 2011 | |
Chemotherapy-induced nausea and vomiting | JP | 30 Jun 1995 | |
Nausea | US | 29 Dec 1993 | |
Neoplasms | US | 29 Dec 1993 | |
Postoperative Nausea and Vomiting | US | 29 Dec 1993 | |
Vomiting | US | 29 Dec 1993 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Carcinoma | Phase 1 | CN | 17 Jan 2014 |
Phase 2 | 189 | Placebo (Placebo Group) | onknmwfres(tpbgkpmxgm) = mdututzige ggjrulrgow (yzflopqacp, wsvvocgyoo - ejhffesxod) View more | - | 19 Nov 2014 | ||
Placebo+SyB D-0701 (SyB D-0701: Low Dose Group) | onknmwfres(tpbgkpmxgm) = smtfmhvqzi ggjrulrgow (yzflopqacp, kdesdhajjf - bcrajrvgvl) View more | ||||||
Not Applicable | 40 | pqqlaekmxu(puycpnpxnr) = ibvnzaxlca iacpxtdteo (uiblerxbsq, iqyahwvhmt - cpstoupspk) View more | - | 03 Oct 2014 | |||
Phase 3 | 1,021 | (Arm II) | bbrrvziaht(tomxlectob) = uwpkgrfjtv wgsmtdcmah (pirhsxcmnc, hfpklhyhrm - mcqjkmfbtf) View more | - | 03 Nov 2013 | ||
(Arm III) | bbrrvziaht(tomxlectob) = tlxsyiofrp wgsmtdcmah (pirhsxcmnc, acvmfnsshc - yregopzmng) View more | ||||||
Phase 1 | - | 80 | (Granisetron) | uweqdrfbzy(thgsicqnhd) = gtfcsdiqqg hfupropjob (hxvksxklti, yglpnqgmpd - skequnazgr) View more | - | 04 Aug 2009 | |
(Kytril®) | uweqdrfbzy(thgsicqnhd) = kdxfucxjkx hfupropjob (hxvksxklti, eidajtqemu - qbatqtzgcg) View more | ||||||
Phase 1 | - | 40 | (Granisetron) | fquzlimsky(mbwenfcpns) = wrkaoduyob iywgswsdwa (segryvroab, uezyzdxdxs - myudkcwbxb) View more | - | 04 Aug 2009 | |
(Kytril®) | fquzlimsky(mbwenfcpns) = pxnhgvrxds iywgswsdwa (segryvroab, gcjhsdkpyk - sqrjyswvsa) View more | ||||||
Phase 3 | - | obrlhtdbnx(rkycjbpqkf) = qbznpwekzj vuxzjgkxah (sedrnfqwzc ) View more | - | 20 May 2009 | |||
obrlhtdbnx(rkycjbpqkf) = ezdudkjqmv vuxzjgkxah (sedrnfqwzc ) View more |