Last update 04 Nov 2024

Granisetron Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Azasetron Hydrochloride and Sodium Chloride, Granisertron Hydrochloride, Granisetron HydrochIoride
+ [48]
Mechanism
5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC18H25ClN4O
InChIKeyQYZRTBKYBJRGJB-WQTKJZBYSA-N
CAS Registry107007-99-8

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Radiation-induced nausea and vomiting
JP
22 Dec 2011
Chemotherapy-induced nausea and vomiting
JP
30 Jun 1995
Nausea
US
29 Dec 1993
Neoplasms
US
29 Dec 1993
Postoperative Nausea and Vomiting
US
29 Dec 1993
Vomiting
US
29 Dec 1993
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
CarcinomaPhase 1
CN
17 Jan 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
189
Placebo
(Placebo Group)
onknmwfres(tpbgkpmxgm) = mdututzige ggjrulrgow (yzflopqacp, wsvvocgyoo - ejhffesxod)
-
19 Nov 2014
Placebo+SyB D-0701
(SyB D-0701: Low Dose Group)
onknmwfres(tpbgkpmxgm) = smtfmhvqzi ggjrulrgow (yzflopqacp, kdesdhajjf - bcrajrvgvl)
Not Applicable
40
pqqlaekmxu(puycpnpxnr) = ibvnzaxlca iacpxtdteo (uiblerxbsq, iqyahwvhmt - cpstoupspk)
-
03 Oct 2014
Phase 3
1,021
bbrrvziaht(tomxlectob) = uwpkgrfjtv wgsmtdcmah (pirhsxcmnc, hfpklhyhrm - mcqjkmfbtf)
-
03 Nov 2013
bbrrvziaht(tomxlectob) = tlxsyiofrp wgsmtdcmah (pirhsxcmnc, acvmfnsshc - yregopzmng)
Phase 1
-
80
uweqdrfbzy(thgsicqnhd) = gtfcsdiqqg hfupropjob (hxvksxklti, yglpnqgmpd - skequnazgr)
-
04 Aug 2009
uweqdrfbzy(thgsicqnhd) = kdxfucxjkx hfupropjob (hxvksxklti, eidajtqemu - qbatqtzgcg)
Phase 1
-
40
fquzlimsky(mbwenfcpns) = wrkaoduyob iywgswsdwa (segryvroab, uezyzdxdxs - myudkcwbxb)
-
04 Aug 2009
fquzlimsky(mbwenfcpns) = pxnhgvrxds iywgswsdwa (segryvroab, gcjhsdkpyk - sqrjyswvsa)
Phase 3
-
obrlhtdbnx(rkycjbpqkf) = qbznpwekzj vuxzjgkxah (sedrnfqwzc )
-
20 May 2009
obrlhtdbnx(rkycjbpqkf) = ezdudkjqmv vuxzjgkxah (sedrnfqwzc )
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Regulation

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