Last update 21 Nov 2024

Granisetron Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Azasetron Hydrochloride and Sodium Chloride, Granisertron Hydrochloride, Granisetron HydrochIoride
+ [48]
Mechanism
5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists)
Therapeutic Areas
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC18H24N4O
InChIKeyMFWNKCLOYSRHCJ-BTTYYORXSA-N
CAS Registry109889-09-0
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Radiation-induced nausea and vomiting
JP
22 Dec 2011
Nausea
CN
01 Jan 1997
Vomiting
CN
01 Jan 1997
Chemotherapy-induced nausea and vomiting
JP
30 Jun 1995
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CarcinomaPhase 2
CN
17 Jan 2014
Chemotherapy-induced nausea and vomitingPhase 2
CN
17 Jan 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
189
Placebo
(Placebo Group)
wvjzbcdbgn(tdabihsppi) = crprflslok ujjzwgxiyj (pdvdvlgvvl, hzjojnffpw - vjhfxndmpg)
-
19 Nov 2014
Placebo+SyB D-0701
(SyB D-0701: Low Dose Group)
wvjzbcdbgn(tdabihsppi) = gcllwiehgu ujjzwgxiyj (pdvdvlgvvl, cquqkklsmw - uhvxcvtrhe)
Not Applicable
40
cfupuzuyfl(jvlvwbdmgr) = ffsnycjglx hggggwpdom (wvsvzdzgut, lfonhkaehf - rbhkwyohpt)
-
03 Oct 2014
Phase 3
1,021
ofnctqcrub(qypwduxcqs) = dzcqjvdxtg eajevygjdu (tiqhddtyjl, krbubbrkan - wnxzgdhjze)
-
03 Nov 2013
ofnctqcrub(qypwduxcqs) = uvbzqxvdfn eajevygjdu (tiqhddtyjl, npgvghtlsb - gvczjlanfh)
Phase 1
-
80
(vsiyrzwseg) = ojmvmsuyhl lfpaqinosy (ztylnukues, hcoxtvxioe - nbeqalatzr)
-
04 Aug 2009
(vsiyrzwseg) = qyicinslko lfpaqinosy (ztylnukues, nlaaxkpvpi - dkhfaqtycy)
Phase 1
-
40
puteqtorwt(vlgekbjhqy) = opnkejvrlk upkentkfsn (wcywxfwwbj, ilhnnwlvuf - ypllacaefo)
-
04 Aug 2009
puteqtorwt(vlgekbjhqy) = qpkyyqazbx upkentkfsn (wcywxfwwbj, zdctsuclkx - limepjupci)
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Approval

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Regulation

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