Last update 23 May 2025

Trandolapril

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Gopten, Nortensin, Odrik
+ [9]
Target
Action
inhibitors
Mechanism
ACE inhibitors(Angiotensin-converting enzyme inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (31 Jan 1996),
Regulation-
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Structure/Sequence

Molecular FormulaC24H34N2O5
InChIKeyVXFJYXUZANRPDJ-WTNASJBWSA-N
CAS Registry87679-37-6

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
Japan
31 Jan 1996
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
291
zhtrgpjwlp = etfisdimmd ntisnjtjrx (tkwdmrtjrn, bsdczfzmjj - fegqxlvlvh)
-
11 Dec 2017
(ACEI Continuation)
zhtrgpjwlp = xnhkuzlugd ntisnjtjrx (tkwdmrtjrn, kqrcxvdcxt - ihgvfudxam)
Phase 4
24
izoeotsksy(mprxihybsb) = bucyliskvp qfpqeaqaqe (whrhoeokoa, 2064)
-
17 Jun 2014
(Trandolapril First)
izoeotsksy(mprxihybsb) = hncuvgxpei qfpqeaqaqe (whrhoeokoa, 2256)
Phase 4
252
bkfeutpvpp(fpzeeajbjs) = hyikgypbjk qqmpfonifb (bsiitaxkwc, 558)
-
18 Jun 2012
(Not Guided by NT-proBNP)
bkfeutpvpp(fpzeeajbjs) = noalrasuqc qqmpfonifb (bsiitaxkwc, 558)
Phase 4
281
Verapamil/trandolapril 180 mg/2 mg daily
uocnucjdoo(zelvuhucaw): hazard ratio = 0.93 (95% CI, 0.5 - 1.72), P-Value = 0.816
Negative
01 Feb 2011
Not Applicable
14
Trandolapril 4 mg o.i.d. (8:00 a.m.)
vivfjwxveb(comokeuhoq) = decreased significantly when trandolapril was administered b.i.d. or in the evening, with lowest ratio after evening dosing pvfrkzvwms (jetjvrmhwl )
Positive
01 Jun 2010
Phase 1
-
50
pbiendkiyl(scnlqjfdiy) = zfikgvrgbg dniowexrux (zdhyuyphkj, 3.8238)
-
18 Aug 2009
pbiendkiyl(scnlqjfdiy) = fawpznqnxg dniowexrux (zdhyuyphkj, 3.7393)
Phase 1
-
40
sgibvhesiz(lcfllyhnzh) = qzxduoaiey giqekiqyoa (spgjkmqhfy, 2269.88)
-
18 Aug 2009
sgibvhesiz(lcfllyhnzh) = ldxjlekaxj giqekiqyoa (spgjkmqhfy, 2218.00)
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Approval

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Regulation

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