AChE inhibitors function by reversibly inhibiting AChE, leading to the accumulation of ACh at synaptic locations, which in turn improves cognitive functions in Alzheimer's disease (AD) patients.
The 5-HT1A receptor is one of the most widely distributed 5-HT receptors, present on the cell bodies and dendrites of 5-HT neurons, situated in the raphe nucleus and the terminal location of 5-HT release.
Tumor Necrosis Factor (TNF) is a protein produced by immune cells in the human body. It plays a crucial role in regulating inflammation and immune responses.