Recent blog posts
Review and Prospects of HDAC Inhibitors
Review and Prospects of HDAC Inhibitors
20 September 2023
HDAC (Histone Deacetylase), otherwise known as a histone deacetylase, is an important type of enzyme involved in the process of histone modifications.
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Progress in the Research of GnRHR Agonists
Progress in the Research of GnRHR Agonists
20 September 2023
GnRHR, or Gonadotropin-Releasing Hormone Receptor, plays a crucial role in the human body's reproductive system.
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Progress in the Research of COX-1 Inhibitors
Progress in the Research of COX-1 Inhibitors
20 September 2023
Cyclooxygenase, also known as Prostaglandin-endoperoxide Synthase, is a bifunctional enzyme with both cyclooxygenase and peroxidase activity.
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Progress in the Research of COMT Inhibitors
Progress in the Research of COMT Inhibitors
20 September 2023
Catechol O-methyltransferase (COMT) is an enzyme responsible for the O-methylation of endogenous neurotransmitters, xenobiotics, and hormones with catechol structures.
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Targeting 5-lipoxygenase - Leukotriene inhibitor
Targeting 5-lipoxygenase - Leukotriene inhibitor
19 September 2023
Leukotrienes are a group of inflammatory mediators produced by the metabolism of arachidonic acid (AA) through the 5-lipoxygenase (5-LO) pathway, featuring a conjugated triene structure of a 20-carbon unsaturated acid.
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Breaking the "Undruggable" Curse: A Discussion on KRAS Inhibitors
Breaking the "Undruggable" Curse: A Discussion on KRAS Inhibitors
19 September 2023
As one of the three major types of genes in the RAS family, the KRAS mutation is one of the most common oncogenic mutations in cancer patients.
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Progress in the Research of MEK Inhibitors
Progress in the Research of MEK Inhibitors
19 September 2023
MEK, or Mitogen-Activated Protein Kinase Kinase, plays a crucial role in the human body as a key component of the MAPK signaling pathway.
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LSD1 inhibitors - A potent inhibitory target for tumor immunotherapy
LSD1 inhibitors - A potent inhibitory target for tumor immunotherapy
19 September 2023
LSD1, also known as lysine-specific demethylase 1A, is an enzyme that plays a crucial role in the regulation of gene expression in the human body.
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Allergy Terminator: Leukotriene Receptor Antagonist
Allergy Terminator: Leukotriene Receptor Antagonist
19 September 2023
Leukotriene antagonists work by blocking the action of leukotrienes, they are mainly used for preventing asthma, controlling allergic rhinitis or allergic reactions.
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Another Potential Stock after PD1 - LAG3 Inhibitors
Another Potential Stock after PD1 - LAG3 Inhibitors
19 September 2023
The Lymphocyte-activation gene-3 (LAG-3) is located on human chromosome 12 (20p13.3), includes 8 exons, and its corresponding cDNA encodes a membrane protein containing 498 amino acids.
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Regulating tumor immune suppression, the therapeutic effect of the new generation CSF-1R inhibitors is encouraging
Regulating tumor immune suppression, the therapeutic effect of the new generation CSF-1R inhibitors is encouraging
18 September 2023
CSF-1 exerts its effects by binding to a receptor called colony stimulating factor 1 receptor (CSF-1R), also known as c-FMS, leading to a signaling pathway cascade.
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Migraine Treatment Medication——CGRP antagonists
Migraine Treatment Medication——CGRP antagonists
18 September 2023
CGRP, or calcitonin gene-related peptide, is a neuropeptide that plays a crucial role in the human body.
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