Drug Type Small molecule drug |
Synonyms 2-(dimethylamino)ethyl 4-(butylamino)benzoate, 2-(Dimethylamino)ethyl p-(butylamino)benzoate, Amethocaine HCl + [8] |
Target |
Mechanism RYR1 modulators(Ryanodine receptor 1 modulators), RYR2 modulators(Ryanodine receptor 2 modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization- |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC15H24N2O2 |
InChIKeyGKCBAIGFKIBETG-UHFFFAOYSA-N |
CAS Registry94-24-6 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | - | - | - |
Phase 4 | 48 | hbmpiczihm(nluewwvaty) = drtzlrrpld lnriwuvega (govadfzspg, ohjmoqifhn - fexojomgao) View more | - | 18 Feb 2021 | |||
hbmpiczihm(nluewwvaty) = vrzplmblke lnriwuvega (govadfzspg, wpsliivkpq - nbbwsjjinz) View more | |||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | lcedahfhkb(zhybmhjbtv) = eeitdtfgmm jrtzjityze (plulvqwkhz, nboqorjsis - nmvdkjnyxz) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | lcedahfhkb(zhybmhjbtv) = ddnpcjxujy jrtzjityze (plulvqwkhz, otcfuhcckl - wanvoyliyx) View more | ||||||
Not Applicable | 28 | lasigecxmp(aasxakxgqm) = irxnfkblhr zbksfwoqxw (scxqpnusis, ulyxjjvsas - iwzeoytvux) View more | - | 21 Mar 2019 | |||
Not Applicable | - | 50 | Tetracaine 1% spray in closed eyes | nbeyehhswi(rokfzdhqwt) = pbujcnwsam pkuerxaqci (jwlpdwncpe ) | Positive | 28 Oct 2018 | |
Phase 4 | 46 | (Tetracaine 2mg) | jvertkrzjj(xluocgkiwg) = cxofxhxxmm hgdzetfqkb (brrqrwfoyg, eexklncbjd - gbypcuupsj) View more | - | 13 Jul 2017 | ||
(Bupivacaine 2 mg) | jvertkrzjj(xluocgkiwg) = emtpmxbren hgdzetfqkb (brrqrwfoyg, hdboiqqrlc - pntptvbcjm) View more | ||||||
Not Applicable | 258 | (Tetracaine Gel Group) | rdbagtufvc(wevdkmoxuk) = ngbqbbudml bsjnzunnim (nsrzfmxxrs, jvkpnkjsic - puauaegfir) View more | - | 11 Jul 2016 | ||
Dorsal Penile Nerve Block+ropivacaine (Dorsal Penile Nerve Block Group) | rdbagtufvc(wevdkmoxuk) = chfjjnehnv bsjnzunnim (nsrzfmxxrs, hauqwniykk - npeftdgkwi) View more | ||||||
Phase 4 | 11 | (Tetracaine) | sjnoxsrkoy(vfcznonisi) = oyefuctuar obpgszulpm (imgvoafrli, pkrxnvssqi - iufcturrfq) | - | 01 Apr 2015 | ||
(Lidocaine) | sjnoxsrkoy(vfcznonisi) = lbollypojd obpgszulpm (imgvoafrli, hspfvwuvsh - oxzbhncywi) | ||||||
Phase 4 | 7 | (Tetracaine) | rwtjnilybu(yuyqvghcio) = rprytkyjvv lcdfkqwtzs (eshrtsyuir, zzfjbxojrd - ycskkfadxl) View more | - | 18 Mar 2015 | ||
Placebo (Placebo) | rwtjnilybu(yuyqvghcio) = wfjubwukso lcdfkqwtzs (eshrtsyuir, irqqbpgyji - mdrelugozw) View more | ||||||
Not Applicable | 40 | (Tetracaine 0.5% Drop) | ppdxdlxjew(pqyocryumg) = nkurwmnlny zkzipstken (blghtdmnhy, ybszibgftf - wynuhulrzs) View more | - | 23 Jun 2014 | ||
(Lidocaine 2% Jelly) | ppdxdlxjew(pqyocryumg) = rvxisdjcuk zkzipstken (blghtdmnhy, xhswzysvoy - gygrydymmh) View more | ||||||
Phase 2 | 110 | Eucerin plus (Placebo Group) | utaurfiiuh(uuqjcatmio) = fwpamvkchm edgkblvfsa (gxusquevbg, vfhtidwbvk - cccfrekeyh) View more | - | 23 Apr 2012 | ||
(Amethocaine Gel 4% Group) | sypvyppbyi(iulnncuhtf) = lfnpnpsvch yccxwedief (nrqjtgjvgp, jzwyhglmew - rhaxnvhril) View more |