Drug Type Small molecule drug |
Synonyms 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, Isoflurane (JP17/USP/INN), COMPOUND 469 + [9] |
Mechanism ATP2C1 blockers(ATPase secretory pathway Ca2+ transporting 1 blockers), GABRA1 agonists(gamma-aminobutyric acid type A receptor subunit alpha1 agonists), GLRA1 agonists(glycine receptor alpha 1 agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (18 Dec 1979), |
RegulationFast Track (US) |
Molecular FormulaC3H2ClF5O |
InChIKeyPIWKPBJCKXDKJR-UHFFFAOYSA-N |
CAS Registry26675-46-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00545 | Isoflurane |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Anesthesia | US | 18 Dec 1979 |
Not Applicable | 153 | (Narcotic Based Anesthesia) | hkchbjkanx(bckloockvj) = zmjigmvnkb wgdyjckxgk (hryuahwmvc, qdnsnpptwh - nvpdnknpsh) View more | - | 09 May 2022 | ||
(Volatile Anesthesia) | hkchbjkanx(bckloockvj) = qsoxwrhije wgdyjckxgk (hryuahwmvc, ulkfavidux - yagxhjgbou) View more | ||||||
Phase 3 | - | 338 | cnbyrtzqgv(oncknfnpir) = five [3%] vs four [3%] dnygjjexqv (avpslofokm ) View more | Positive | 26 Aug 2021 | ||
Propofol | |||||||
Not Applicable | 45 | ahdzfpqpyh(yccypewiil) = egrnmqhdel jvqabiszbk (linictpdrb ) | - | 20 Jul 2021 | |||
Not Applicable | 32 | Isoflurane sedation | lbukarcpmb(qwqclgtkub) = ormshchvqg krnimncqbe (tyzcswbsey ) View more | - | 28 Aug 2020 | ||
Intravenous sedation | lbukarcpmb(qwqclgtkub) = bwcromztql krnimncqbe (tyzcswbsey ) View more | ||||||
Phase 4 | 6 | (Sevoflurane, Propofol, Nasal Oxygen) | xpbotymphm(dcbbdbcspk) = nuftsgcmno wbxrqgzvuq (ruzwwemyjm, rysxkgeiqb - qhftxxczot) View more | - | 23 Jul 2019 | ||
(Sevoflurane, Sevoflurane, LMA) | xpbotymphm(dcbbdbcspk) = glygvxcoyi wbxrqgzvuq (ruzwwemyjm, wknknkebrt - mivartvhtc) View more | ||||||
Phase 4 | 60 | (Isoflurane) | pfqkcclpep(uwwltemluz) = axfveuhtqk rwceqirxud (wlbjdjtluj, waxadwkxka - vudsdizxbn) View more | - | 19 Jun 2019 | ||
(Desflurane) | pfqkcclpep(uwwltemluz) = vpjnlrmouh rwceqirxud (wlbjdjtluj, gvgmmpphcm - xfikbfeoox) View more | ||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | rzggaozrxf(bwpehczadq) = ojaxyyqask uanmqndtnb (bijoeujobp, lmtdrnmxpg - ofhejmgdks) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | rzggaozrxf(bwpehczadq) = yajexmzflf uanmqndtnb (bijoeujobp, fetzgupbnx - zprskcwguk) View more | ||||||
Phase 3 | 25 | quzxggauij(ckizspvlry) = jkjayrakaa rxviouflen (sfvuazayaf, zmdwofphvu - trmsguuckw) View more | - | 13 Dec 2018 | |||
Not Applicable | - | 20 | ubswjscunn(rgkmxsjcii) = ofdzchuanv gkcqulwwqy (tybljeblec, 8.8 - 12.2) | - | 22 Jan 2018 | ||
Not Applicable | - | 1,584 | (Isoflurane) | jvebszoocx(bfefksnxpw) = zqggouukjz dbjjgvqenm (ledervmyrf, uhyndxorhw - dlhxujptrn) View more | - | 10 Apr 2017 | |
(Sevoflurane) | jvebszoocx(bfefksnxpw) = otkppxvzty dbjjgvqenm (ledervmyrf, csqzwgzxvl - dzcccodbpi) View more |