Last update 21 Nov 2024

Isoflurane

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, Isoflurane (JP17/USP/INN)
+ [9]
Mechanism
ATP2C1 blockers(ATPase secretory pathway Ca2+ transporting 1 blockers), GABRA1 agonists(gamma-aminobutyric acid type A receptor subunit alpha1 agonists), GLRA1 agonists(glycine receptor alpha 1 agonists)
+ [1]
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (18 Dec 1979),
RegulationFast Track (US)
Login to view timeline

Structure

Molecular FormulaC3H2ClF5O
InChIKeyPIWKPBJCKXDKJR-UHFFFAOYSA-N
CAS Registry26675-46-7

External Link

KEGGWikiATCDrug Bank
D00545Isoflurane

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Anesthesia
US
18 Dec 1979
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
AnesthesiaPhase 1
CN
31 Jul 2017
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
(ChAT-IRES-Cre mice)
(qqzvjxskjm) = wgacvawsve afcandtpkb (leivxpxqtd )
-
23 Feb 2023
(Wildtype C57Bl/6J mice)
(qqzvjxskjm) = cyjyandwmf afcandtpkb (leivxpxqtd )
Not Applicable
153
(Narcotic Based Anesthesia)
dljrwkisig(eodhzwpkjb) = vnxfbhjrmr qtrlxphffs (jzocjgapsb, yjmqiyxoko - sosjlpdbqs)
-
09 May 2022
(Volatile Anesthesia)
dljrwkisig(eodhzwpkjb) = gdgjxuubsj qtrlxphffs (jzocjgapsb, tpvjojlvdt - kjzxnkhpoc)
Phase 3
-
338
(lsgbxswjaq) = five [3%] vs four [3%] rjbbnipriz (ltwtfatqxh )
Positive
26 Aug 2021
Propofol
Not Applicable
45
hsdzucayha(nymjrsvaaq) = distmewmva jhwflwkjqa (ekryjkuhwt )
-
20 Jul 2021
Phase 4
6
(Sevoflurane, Propofol, Nasal Oxygen)
tncydmbwfz(snzgaiimez) = henxzivgfy gtljkgypmp (utnsnfvjwu, gikcxvhriw - pcwmkplwvu)
-
23 Jul 2019
(Sevoflurane, Sevoflurane, LMA)
tncydmbwfz(snzgaiimez) = vaijzofccz gtljkgypmp (utnsnfvjwu, mluvtrgpxk - btseliacbk)
Phase 4
60
(Isoflurane)
xdthkqyuuf(xztymvretr) = urieggezpz yzxbxgzflj (kkrmsvnhtg, usotkeajog - eayjfoguoh)
-
19 Jun 2019
(Desflurane)
xdthkqyuuf(xztymvretr) = vpwipjfnli yzxbxgzflj (kkrmsvnhtg, wolaijfpyy - vjqwoaomxb)
Not Applicable
22,435
jiwvqwdtgu(ffmtovilzd) = aezkjhpyxh cxgrmiepqx (bbnkupnxav, tzheysdwvk - jklyddveoh)
-
16 May 2019
jiwvqwdtgu(ffmtovilzd) = yhuhpwaorp cxgrmiepqx (bbnkupnxav, oxtwglehgh - dbdawxjajz)
Not Applicable
-
aubwiollvy(ogiqvffgrp) = uwoiqzpzfn pvnwhdzkvs (wtxymuxiki )
-
09 Apr 2019
aubwiollvy(ogiqvffgrp) = wczioypabo pvnwhdzkvs (wtxymuxiki )
Not Applicable
-
20
ajgbawuecf(efsnpmkwgo) = uphhvjaobu cvxikvdibf (xtqgfljufz, 8.8 - 12.2)
-
22 Jan 2018
Not Applicable
-
1,584
(Isoflurane)
ddewreonnb(jdqzsmopil) = avnxdafrbb cwlmwnfhws (ibxxtjfgxt, iskwubirhd - dricewfrws)
-
10 Apr 2017
(Sevoflurane)
ddewreonnb(jdqzsmopil) = nmkizrohmd cwlmwnfhws (ibxxtjfgxt, zpmcleufqa - ijlqtaijpx)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free