Drug Type Small molecule drug |
Synonyms hydroxyethyl starch, 羟乙基淀粉130/0.4氯化钠注射液, Bolben infusion 6% + [7] |
Target- |
Mechanism- |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date DE (25 Apr 2000) |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
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- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
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Massive hemorrhage | Phase 3 | JP | 01 May 2010 | |
Hemorrhage | Phase 3 | JP | 01 Nov 2009 | |
Hypovolemia | Phase 3 | JP | 01 Nov 2009 | |
Shock, Septic | Phase 3 | DE | 01 Apr 2003 | |
Shock, Septic | Phase 3 | DE | 01 Apr 2003 |
Not Applicable | 85 | Human albumin (Human Albumin) | tlcvptqzsf(glfhsiyvxa) = fhtrfjfpmu fkztplffmg (xhyjfsgddx, fsjcwakoxv - fmoxfihoyh) View more | - | 01 Feb 2024 | ||
Hydroxyethyl starch (Hydroxyethyl Starch) | tlcvptqzsf(glfhsiyvxa) = zhecfgckjg fkztplffmg (xhyjfsgddx, cmeyjtbnew - wnkwewehud) View more | ||||||
Phase 3 | - | 149 | (HES 130/0.4 (Voluven)) | aaxoqbnerb(uylwqeqpzx) = xwgmymlxfs onzmtzhics (azysntmjrz, nbuxnkecbh - aqegyumldr) View more | - | 14 Feb 2023 | |
human albumin 5% (Human Albumin 5%) | aaxoqbnerb(uylwqeqpzx) = vxohdzinsp onzmtzhics (azysntmjrz, duuoredjzy - mrcylwcvri) View more | ||||||
Not Applicable | 22,435 | Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Usual Care Group) | hgqhwirfbq(yzwoqkdwpc) = pqlggxeupo kuorqkfhps (npjuwnpzpu, urksofmmik - ezbiethpke) View more | - | 16 May 2019 | ||
Central neuraxial anesthesia+Glycopyrrolate+dopamine+Hydroxyethyl starch solutions+Epinephrine+desflurane+bupivacaine+Sodium Chloride 0.9%+propofol+atropine+Ephedrine+Isoflurane+Dobutamine+Vasopressin+Isoproterenol+norepinephrine+Prilocaine+Benzocaine+Procaine+Terlipressin+Tetracaine+ropivacaine+Articaine+levobupivacaine+Milrinone+phenylephrine+Sevoflurane+Mepivacaine+lidocaine+Chloroprocaine (Hypotension Decision Support) | hgqhwirfbq(yzwoqkdwpc) = dhfxamsuko kuorqkfhps (npjuwnpzpu, gyyovekfgp - luezmohlwg) View more | ||||||
Not Applicable | - | 2,000 | (Patients who did not receive HES) | aubadshzay(xxrvkpbtar): hazard ratio = 1.24 (95% CI, 1.14 - 1.35) View more | - | 01 Jan 2019 | |
(Patients exposed to HES) | |||||||
Phase 3 | - | 7,000 | vlbqhhylmt(faryfqvyng) = hidbyctcme tovuwupyxd (hvtnwzpowl ) | - | 01 Oct 2016 | ||
Saline | vlbqhhylmt(faryfqvyng) = vderljgajt tovuwupyxd (hvtnwzpowl ) | ||||||
Not Applicable | 120 | Lactate Ringers (Lactate Ringers) | ochwzgbiqf(gnlqbnubsj) = sbkhccxqni ijifeeyepl (zdnfseierl, zmepmllggh - awzjsrkbvn) View more | - | 24 Mar 2016 | ||
Hydroxyethyl Starch (Hydroxyethyl Starch) | ochwzgbiqf(gnlqbnubsj) = gagojdttoz ijifeeyepl (zdnfseierl, tdnqvurcrw - jxzzwgbmvg) View more | ||||||
Phase 4 | - | 40 | giuscfxwcg(pdnhvmuaoj) = ebjoyqpdwq irpynmsqmo (zxdludldli ) | - | 01 Mar 2015 | ||
Saline 0.9% | giuscfxwcg(pdnhvmuaoj) = mjudimlqci irpynmsqmo (zxdludldli ) | ||||||
Phase 3 | 804 | bgsjrbxljc(ugofykzdce) = uylwyejbhg lnnbllzgik (xslllagcce ) View more | - | 01 Jul 2014 | |||
Ringer's acetate | bgsjrbxljc(ugofykzdce) = wqibmrtgwl lnnbllzgik (xslllagcce ) View more | ||||||
Phase 3 | - | 7,000 | 6% HES with a molecular weight of 130 kD and a molar substitution ratio of 0.4 (130/0.4, Voluven) in 0.9% sodium chloride | hbmdkcccgs(cazsqphlgm) = klyvmbvosa avgchsbpsr (lwxuisdare ) View more | - | 15 Nov 2012 | |
hbmdkcccgs(cazsqphlgm) = bucrimxcmw avgchsbpsr (lwxuisdare ) View more | |||||||
Phase 3 | 804 | tfxaxhkoyk(nnbnbwuexg) = wrpypeemil ruufdhpcix (zsdtaokufl ) View more | Negative | 12 Jul 2012 | |||
Ringer's acetate | tfxaxhkoyk(nnbnbwuexg) = jmlsbxkiwc ruufdhpcix (zsdtaokufl ) View more |