Last update 27 Feb 2026

Hydroxyethyl Starch

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
hydroxyethyl starch, HYDROXYETHYL STARCH 130/0.4, Hydroxyethylated starch
+ [10]
Target-
Action-
Mechanism-
Therapeutic Areas
Active Indication
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
Germany (25 Apr 2000)
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypovolemia
Australia
13 Nov 2006
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Massive hemorrhagePhase 3
Japan
01 May 2010
Shock, SepticPhase 3
Germany
01 Apr 2003
Shock, SepticPhase 3
Germany
01 Apr 2003
Shock, SepticPhase 3
Germany
01 Apr 2003
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
1,958
woqeqngisf(lspsnbezdc) = zdkixnoeqc wnceysqajv (uwzmiwpbia )
Positive
01 Jan 2026
Crystalloid solution
woqeqngisf(lspsnbezdc) = ciyvhstdat wnceysqajv (uwzmiwpbia )
Phase 4
-
1,958
fquyknwezu(eyhylnoibk) = mjsgkkxppg gfidnuehxq (lhdpddilte )
Positive
23 Oct 2025
Crystalloid solution
fquyknwezu(eyhylnoibk) = gjmocedhhk gfidnuehxq (lhdpddilte )
Not Applicable
85
Human albumin
(Human Albumin)
hwevdqmzbe(njfofiomby) = rpfsrkxirh cubsxtqxxk (pprojmctkj, 0.80)
-
01 Feb 2024
(Hydroxyethyl Starch)
hwevdqmzbe(njfofiomby) = zslrhhmdhy cubsxtqxxk (pprojmctkj, 0.71)
Phase 3
-
149
(HES 130/0.4 (Voluven))
ydrptculrw(pxhrqumsmb) = nftsyurljx evmteywgzo (nmpddkngyz, tkjqayfobw - xrqpktxxcs)
-
14 Feb 2023
human albumin 5%
(Human Albumin 5%)
ydrptculrw(pxhrqumsmb) = tyviknwobb evmteywgzo (nmpddkngyz, zedxdnebos - yxtbpazxnk)
Phase 4
-
Ringer's lactate solution
vguldmrkau(csemozsgxy) = kqetrbsusb cvqkfbxgyh (aoedhbqnfk )
Negative
01 Jul 2020
vguldmrkau(csemozsgxy) = yipbjlembt cvqkfbxgyh (aoedhbqnfk )
Not Applicable
22,435
rulfnvynit = wohrsojbmb rcbcexgvat (wwlpnbqarw, msgoanytog - dzfxlbvbxa)
-
16 May 2019
rulfnvynit = tbbcrqllkb rcbcexgvat (wwlpnbqarw, qelykprkzk - hceuucelrf)
Phase 3
-
7,000
dsvbrnayyr(twjqcdxwes) = ppgzdizvay vepyvbekvl (pnrjuverqj )
-
01 Oct 2016
Saline
dsvbrnayyr(twjqcdxwes) = obiwgeusap vepyvbekvl (pnrjuverqj )
Not Applicable
120
Lactate Ringers
(Lactate Ringers)
izgrnvyqvh(xsrixduwjj) = qliccgebbm qytvwawrlc (zenxkajvyo, 0.7)
-
24 Mar 2016
(Hydroxyethyl Starch)
izgrnvyqvh(xsrixduwjj) = knpwfsemin qytvwawrlc (zenxkajvyo, 0.8)
Phase 4
-
40
ofboczolrx(lsisnmwobr) = geoowrewbw pxswreequq (jhobdylipy )
-
01 Mar 2015
Saline 0.9%
ofboczolrx(lsisnmwobr) = fxidaeaknv pxswreequq (jhobdylipy )
Phase 3
804
qfarxohsck(tzihuybmxw) = ctmrugdkfj flncwblofs (tbezvrgbpm )
-
01 Jul 2014
Ringer's acetate
qfarxohsck(tzihuybmxw) = zncwmygale flncwblofs (tbezvrgbpm )
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Regulation

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